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Prion Diseases: Transmissible Spongiform Encephalopathies (TSEs)

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General & Overviews
  • Prion Diseases
    GeneReviews

    Includes diagnosis, clinical description, prevalence, differential diagnosis, management, genetic counseling, molecular genetics and resources.


BSE: Bovine Spongium Encephalopathy (Mad Cow Disease)
  • The Brain Eater (NOVA)
    Companion Web site to the NOVA program "The Brain Eater," originally broadcast on February 10, 1998. This program retraces the scientific sleuthing that linked mad cow disease in cattle to a related brain disease in humans.
  • BSE Information at UIUC
    University of Illinois at Urbana-Champaign

    Contains two sections: Scientific ’In Depth’ section and a slide show section The ’In Depth’ section contains:

    Introduction: Description of spongiform encephalopathies, timeline and definition of terms

    BSE: Signs, epidemiology, location, infectivity, clinical tests relating to BSE; Graphics showing the means of transmission; Plots of the BSE epidemic; UK and US regulations aimed to control and eradicate BSE

    Prions: Prions are the causitive agent for all TSEs; Prion description, protein processing, structure, mutations, species differences, stability; Prion transmission, transmission barriers, concerns; Methods for identifying prion strains and tests

    Human TSE: Description, causes and symptoms of human TSEs including vCJD (nvCJD); Saftety concerns of food and the US blood supply; Graphics illustrating incidence, location and trends of human TSE; Illustration on the route of transmission for human TSEs; Graphics illustrating the function and structure of the human brain and the sites of TSE effects

    TSE of other species: Information of sheep scrapie and TSEs of cats, wild deer, elk, pets and mink

    Other Information: Links to other BSE sites, to UIUC sites and to the authors

  • BSEinfo.org
    This site is funded in part by America’s Beef Producers through the Beef Checkoff Program and managed by the National Cattlemen’s Beef Association on behalf of the Cattlemen’s Beef Board and State Beef Councils. This site is funded in part by National Cattlemen’s Beef Association member dues.

    Industry news; FAQs; scientific resource; beef industry facts; links

  • How Mad Cow Disease Works
    HowStuffWorks.com

    Introduction; What is Mad Cow Disease?; How BSE works; Secret agent; The Prion hypothesis; control & prevention; more information

  • Mad-Cow-Facts.com
    Presented by the Center for Global Food Issues.

    About Mad Cow; News & analysis; links & resources; FAQs

  • OIE: Bovine Spongiform Encephalopathy (BSE)
    Office International des Epizooties (OIE)/ World Organization for Animal Health.

    Map of Geographical Distribution of Countries that reported BSE Confirmed Cases since 1989 ;

    Information on the number of BSE cases reported in the United Kingdom and in the world (excluding the United Kingdom) in imported or indigenous cattle, and Countries/Territories that have reported BSE cases in imported animals only

    Information on annual incidence rate of BSE, by country, since 1989.


CJD: Creutzfeld-Jakob Disease
  • MedlinePlus: Crutzfeldt-Jakob Disease
    MedlinePlus brings together authoritative information from NLM, the National Institutes of Health (NIH), and other government agencies and health-related organizations.

    News; Overviews; prevention/screening; specific conditions; related issues; clinical trials; genetics; research; organziations; law & policy; statistics

  • National Creutzfeldt-Jakob Disease Surveillance Unit
    The incidence of Creutzfeldt-Jakob disease (CJD) is monitored in the UK by the National CJD surveillance unit based at the Western General Hospital in Edinburgh, Scotland. The unit brings together a team of clinical neurologists, neuropathologists and scientists specialising in the investigation of this disease. This document is intended to summarise the research in progress at the CJD unit and also provide some background information about CJD and other human spongiform encephalopathies.

CWD: Chronic Wasting Disease
  • APHIS.USDA: Chronic Wasting Disease
    Animal and Plant Health Inspection Service.

    History; distribution; state information; research; news & updates; diagnostics; photos; interagency plans

    • Understanding Chronic Wasting in Wisconsin
      Pelej, Jennifer. 2002

      This publication was produced by the Department of Natural Resources with assistance from Interagency CWD Taskforce to assist hunters and landowners in Wisconsin’s Chronic Wasting Disease Management Zone better understand chronic wasting disease and its management.


Kuru
  • Kuru
    Janson Paul A.

    eMedicine; October 15, 2005

  • Kuru Information Page
    National Institute of Neurological Disorders and Stroke (NINDS).

    Overview, treatment, prognosis, research



Page Coordinator: Katherine Chew chewx002@umn.edu
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